Tšimoloho ea boko ba motho e ea hlaka ka lebaka la tlhapi ea likokoana-hloko

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Phuputso ea DNA ea lebone la tlhapi ea tlhapi ea khale e se nang mohlahare e ile ea lumella litsebi tsa liphatsa tsa lefutso tsa Russia ho fumana karabo ea potso ea hore na baholo-holo ba rona ba fumane boko bo rarahaneng le lehata joang.

Ho sibolloa ha liphatsa tsa lefutso tse ikhethang, tsoelo-pele ea tsona e fileng baholo-holo ba rona lehata le boko, ho hlalositsoe koranteng Scientific Reports. Ho ea ka Andrei Zaraisky, ea emelang Setsi sa Bioorganic Chemistry ea Russian Academy of Science, phatsa ea lefutso ea Anf / Hesx1 e fumanoe leboneng, e leng lesapo la mokokotlo la khale ka ho fetisisa le phelang. Mohlomong, ke ponahalo ea lefutso lena e ileng ea fetoha phetoho eo kamora moo ponahalo ea boko bo nang le lesapo la mokokotlo e ileng ea khonahala.

E 'ngoe ea likarolo tsa bohlokoahali tse khethollang liphoofolo tse nang le lesapo la mokokotlo ho tsoa ho tse se nang lesapo la mokokotlo ke boteng ba boko bo rarahaneng, bo tsoetseng pele. Ka hona, molemong oa ho sireletsa lisele tse thata tsa methapo hore li se ke tsa senyeha, ho na le selateng se thata se sireletsang. Empa hore na khetla ena e hlahile joang, le se hlahileng pejana - cranium kapa boko - e ntse e sa tsejoe mme e lula e le taba e bakang khang.

Ba tšepile ho fumana karabo ea potso ena, boramahlale ba hlokometse nts'etsopele, ts'ebetso le boteng ba liphatsa tsa lefutso bakeng sa myxins le mabone a lebone, e leng litlhapi tsa khale ka ho fetesisa. Ho ea ka bo-ramahlale, litlhapi tsena tse se nang mohlahare li tšoana haholo le likokoana-hloko tsa pele tse neng li lula leoatleng le ka sehloohong la Lefatše lilemong tse ka bang limilione tse 400-450 tse fetileng.

Ha ba ithuta mosebetsi oa liphatsa tsa lefutso mahe a emeng, Zaraisky le basebetsi-'moho le eena ba ile ba khona ho fana ka leseli le itseng mabapi le ho iphetola ha liphoofolo tse nang le lesapo la mokokotlo, tseo, kamoo ho tsejoang, batho e leng ba tsona. Hona joale bafuputsi ba ntse ba etsa qeto ea hore na ke liphatsa life tsa lefutso tse ka har'a DNA ea liphoofolo tse nang le lesapo la mokokotlo le tseo e seng tsa likokoana-hloko.

Ho ea ka bo-ramahlale ba Russia, morao koana ka 1992, ba ile ba khona ho fumana liphatsa tsa lefutso tse khahlisang (Xanf) ho DNA ea mahe a emolisitsoeng, a neng a supa kholo ea bokantle ba lesea le sa tsoa emoloa, ho kenyeletsoa sefahleho le boko. Joale ho ile ha fanoa ka maikutlo a hore ke lefutso lena le ka behang kholo ea boko le lehata le lesapo la mokokotlo. Empa maikutlo ana ha aa ka a fumana tšehetso, hobane liphatsa tsa lefutso li ne li le sieo ho li-myxin le mabone - li-vertebrate tsa khale ka ho fetisisa.

Empa hamorao lefutso lena le ile la fumanoa ho DNA ea litlhapi tse boletsoeng ka holimo, leha e le ka sebopeho se fetotsoeng hanyane. Ho nkile boiteko bo matla ho tseba ho ntša Hanf e sa bonahaleng mahe a emolisitsoeng le ho paka hore e sebetsa joalo ka analog ea eona ho DNA ea batho, lihoho le likokoana-hloko tse ling.

Ho fihlela sena, boramahlale ba hlahisitse mahe a emeng a mabone a Arctic. Kamora moo, ba emetse ho fihlela motsotso oo lihlooho tsa bona li qalang ho hlahisa, ebe ba ntša boima ba limolek'hule tsa RNA ho eona. Limolek'hule tsena li hlahisoa ke lisele ha li "bala" liphatsa tsa lefutso. Ts'ebetso ena e ile ea fetoha 'me bo-rasaense ba bokella likhoele tse ngata tse khuts'oane tsa DNA. Ebile, ke likopi tsa liphatsa tsa lefutso tse sebetsang haholo mahe a embry.

Ho ile ha ba bonolo haholo ho hlahloba tatellano e joalo ea DNA. Ho ithuta tatellano ena ho file bo-rasaense monyetla oa ho fumana mefuta e ka bang mehlano ea liphatsa tsa lefutso tsa Xanf, tseo e 'ngoe le e' ngoe ea tsona e nang le litaelo tse ikhethang bakeng sa protheine. Liphetolelo tsena tse hlano ha li fapane le tse fumanoeng 'meleng oa lihoho lilemong tse 90 tse hole.

Mosebetsi oa liphatsa tsa lefutso tsena ka mabone o ile oa tšoana le oa lekhetho la DNA ea likokoana-hloko tse tsoetseng pele haholoanyane. Empa ho ne ho e-na le phapang e le 'ngoe: lefutso lena le ile la kenyelletsoa mosebetsing hamorao haholo. Ka lebaka leo, mahata a hlooho ea mabone le boko li nyane.

Ka nako e ts'oanang, ho tšoana ha sebopeho sa lefutso la lebone la lebone la Xanf le lefutso la "senqanqane" Anf / Hesx1 ho bonts'a hore lefutso lena, le hlahileng lilemo tse ka bang limilione tse 550 tse fetileng, le supa boteng ba libopuoa tse nang le lesapo la mokokotlo. Ho fetisisa ka etsahala hore ebe, e ne e le e mong oa lienjini tse ka sehloohong tsa ho iphetola ha liphoofolo tse phelang ka tlhaho le batho ka ho khetheha.

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